As one considers the concept of natural selection with respect to modern science, it is manifest the human mind has the capacity to learn virtually anything. This concept, termed neuroplasticity, reflects the fact that performing an action fires specific neurons relative to that action. Whether that’s putting a ball in a cup or nuclear physics, […]
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One of the reasons the human body is so mysterious is because it is a highly coupled system. A coupled system responds as a whole anytime a single subsystem is changed. Examples of this phenomenon include how psychological stress can lead to problems in other systems of the body such as the digestive system. In […]
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In medicinal chemistry, one often must compromise between absorption, distribution, metabolism, and excretion (ADME) properties and affinity to a certain biological target. This is often a great challenge due to the limited chemical combinations which can yield a high affinity molecule for a target… but what if you had a protein with a very wide […]
When starting a new pharmaceutical chemistry project, there are several common approaches. In my opinion, the most interesting is to take a natural product with known therapeutic properties and begin modifying its structure. This strategy has yielded life saving, world changing medicines including the penicillin based family of antibiotics. Another strategy is to simply perform […]
The future of drug discovery Mankind will always be seeking to create molecular medicines which can solve the health issues we face. Chemical technology is the primary force which can make mankind more healthy, productive, and content as we proceed past our biological prime. Discovering drugs which can do this is thus one of the […]